Sildenafil Treats Antidepressant Sexual Side Effects

Study offers expect people taking newer antidepressants:

People experiencing antidepressant-associated impotence could find hope in a very study from the drug Sildenafil (Viagra). In a six-week, randomized study of 90 men with sexual negative effects from antidepressants, 54.5% of these addressed with Sildenafil showed improvement, based on the January 1, 2003 issue from the Journal from the American Medical Association (JAMA).

The participants in the study were 90 men receiving treatment for major depressive disorder (MDD) with serotonin reuptake inhibitor (SRI) antidepressants at certainly one of three outpatient medical centers in the United States. To be inside study, the men were required to maintain remission from depression or even be experiencing erectile dysfunction linked to the treatment with SRI antidepressants. Researchers used criteria through the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) to define antidepressant-associated erectile dysfunction (AASD). Participants in the study were required to be experiencing impotence due to at least one in the following: male impotence (ED); inability to provide an orgasm; and/or ejaculatory delay with a minimum of ten mins.

โดจิน taken by participants in the study were the SRI antidepressants: citalopram (Celexa), clomipramine (Anafranil), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Tofranil), nefazodone (Serzone), paroxetine (Paxil), sertraline (Zoloft), and venlafaxine (Effexor). The researchers mention that 30% to 70% of individuals taking these SRIs (mainly for depressive and panic attacks) experience sexual unwanted effects, and nearly 90% of those with sexual side effects will stop treatment using the antidepressants because of this. Clearly, solutions because of these unwanted effects are important for successful treatment with SRIs to keep.

The study lasted for about six weeks. Of the 90 participants, 45 received 50 mg of Sildenafil (Viagra) and 45 got a placebo. Participants were advised to look at one pill approximately one hour before intercourse but weren’t take multiple pill every day.
The results in the study show Sildenafil (Viagra) to become promising choice for the various people experiencing antidepressant sexual unwanted side effects. Using several questionnaires to measure results, researchers found out that 54.5% of participants taking Sildenafil were “much or greatly improved” as compared to 4.4% of people taking the placebo. Although Sildenafil (Viagra) is approved by the Food and Drug Administration (FDA) to treat erectile dysfunction, researchers found out that participants experiencing other sorts of impotence also showed improvement. Additionally, researchers found out that patients remained in remission from depression while taking Sildenafil, showing this treatment would not interfere while using depression treatment.